Clear Sky Science – Articles (en)

2026-04-09

Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor

2026-03-23

Design and evaluation of a custom circulating tumour DNA assay to detect endometrial cancer recurrence

2026-03-06

Lactylation as a metabolic-epigenetic switch in cancer: dual roles in cell death resistance and therapeutic vulnerability

2026-03-06

Functional genomics integration of glycolysis-related gene networks reveals prognostic biomarkers and immune microenvironment regulation in breast cancer

2026-03-03

Gene driven analytical learning model for accurate breast cancer diagnosis

2026-02-28

Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma

2026-02-27

Prospective multicenter study of ctDNA versus tumor tissue guiding FGFR-targeted therapy in metastatic urothelial cancer

2026-02-27

Combining tissue-derived microRNAs with clinical risk models for prediction of HCC recurrence after liver transplantation: A proof-of-concept study

2026-02-27

Genetic analysis of key players in PI3K signaling cascade of colorectal carcinoma

2026-02-26

Clinical and molecular characteristics of Class II and III BRAF mutations in colorectal cancer

2026-02-26

Tumor genomics in patients younger than 40 years of age with metastatic breast cancer

2026-02-26

Genomic landscape and clinical impact of BRCA1/2 pathogenic variants in metastatic castration-resistant prostate cancer

2026-02-25

SexTumorDB: a comprehensive resource of sex-dependent tumor landscape at single-cell resolution

2026-02-25

Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies

2026-02-24

Concordance analysis of DNA and RNA profiling: The MD Anderson IMPACT2 study in precision oncology

2026-02-23

Integrating liquid biopsy and mutational signatures to advance precision oncology

2026-02-19

The consensus molecular subtypes of esophageal squamous cell carcinoma

2026-02-17

Dysregulated expression of cell cycle regulators CDC20, PLK1, BUB1, CDC45, CDCA5 in pancreatic ductal adenocarcinoma

2026-02-14

Kinic index: an artificial intelligence-driven predictive model and multitarget drug discovery framework for hepatocellular carcinoma patients

2026-02-13

Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types

2026-02-10

Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

2026-02-08

A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice

2026-02-08

Dual pancreatic carcinomas: clonally related or independent primaries?

2026-02-05

Integrative analyses of metastatic cancer transcriptome reveal clinically distinct cellular States and ecosystems

2026-02-05

Liquid biopsies in precision oncology for older adults with cancer

2026-01-30

A unified framework for pre-screening and screening tools in oncology clinical trials

2026-01-27

Common gene mutations in 103 authenticated colorectal cancer cell lines

2026-01-21

An interpretable deep learning model for predicting endometrial cancer molecular subtypes from H&E-stained slides

2026-01-19

The Knowledge Connector decision support system for multiomics-based precision oncology

2026-01-19

Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers

2026-01-16

Translational evaluation of BUB1B as a precision medicine biomarker for hepatocellular carcinoma

2026-01-16

Spatial transcriptomics reveals molecular heterogeneity and subtype-specific therapeutic targets in small cell lung cancer

2026-01-14

Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples

2026-01-13

ONCOPLEX: an oncology-inspired hypergraph model integrating diverse biological knowledge for cancer driver gene prediction

2026-01-11

Informed spatially aware patterns for multiplexed immunofluorescence data

2026-01-06

PRECISION ONCOLOGY ARTICLES

Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor

Design and evaluation of a custom circulating tumour DNA assay to detect endometrial cancer recurrence

Lactylation as a metabolic-epigenetic switch in cancer: dual roles in cell death resistance and therapeutic vulnerability

Functional genomics integration of glycolysis-related gene networks reveals prognostic biomarkers and immune microenvironment regulation in breast cancer

Gene driven analytical learning model for accurate breast cancer diagnosis

Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient pleural mesothelioma

Prospective multicenter study of ctDNA versus tumor tissue guiding FGFR-targeted therapy in metastatic urothelial cancer

Combining tissue-derived microRNAs with clinical risk models for prediction of HCC recurrence after liver transplantation: A proof-of-concept study

Genetic analysis of key players in PI3K signaling cascade of colorectal carcinoma

Clinical and molecular characteristics of Class II and III BRAF mutations in colorectal cancer

Tumor genomics in patients younger than 40 years of age with metastatic breast cancer

Genomic landscape and clinical impact of BRCA1/2 pathogenic variants in metastatic castration-resistant prostate cancer

SexTumorDB: a comprehensive resource of sex-dependent tumor landscape at single-cell resolution

Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies

Concordance analysis of DNA and RNA profiling: The MD Anderson IMPACT2 study in precision oncology

Integrating liquid biopsy and mutational signatures to advance precision oncology

The consensus molecular subtypes of esophageal squamous cell carcinoma

Dysregulated expression of cell cycle regulators CDC20, PLK1, BUB1, CDC45, CDCA5 in pancreatic ductal adenocarcinoma

Kinic index: an artificial intelligence-driven predictive model and multitarget drug discovery framework for hepatocellular carcinoma patients

Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types

Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice

Dual pancreatic carcinomas: clonally related or independent primaries?

Integrative analyses of metastatic cancer transcriptome reveal clinically distinct cellular States and ecosystems

Liquid biopsies in precision oncology for older adults with cancer

A unified framework for pre-screening and screening tools in oncology clinical trials

Common gene mutations in 103 authenticated colorectal cancer cell lines

An interpretable deep learning model for predicting endometrial cancer molecular subtypes from H&E-stained slides

The Knowledge Connector decision support system for multiomics-based precision oncology

Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers

Translational evaluation of BUB1B as a precision medicine biomarker for hepatocellular carcinoma

Spatial transcriptomics reveals molecular heterogeneity and subtype-specific therapeutic targets in small cell lung cancer

Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples

ONCOPLEX: an oncology-inspired hypergraph model integrating diverse biological knowledge for cancer driver gene prediction

Informed spatially aware patterns for multiplexed immunofluorescence data

Real-world clinical utility of comprehensive genomic profiling in advanced solid tumors