2026-03-31 A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
2026-03-14 Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B
2026-03-13 Gut microbiota modulation via repeated donor fecal transplantation improves motor and gastrointestinal symptoms in drug-naïve Parkinson’s disease: a randomized phase 2 trial
2026-02-21 Plasma brain-derived tau: analytical and clinical validation of the first commercial immunoassay
2026-02-20 Variants in MTNAP1 underlie a neurodegenerative disorder by impairing mitochondrial stability
2026-02-16 Decoupling phase separation and fibrillization preserves activity of biomolecular condensates
2026-02-11 Free water in the external globus pallidus predicts mild cognitive impairment in Parkinson’s disease and is associated with serum neurofilament light chain levels
2026-02-11 Scaffold-client behavior and structural organization in multicomponent protein condensates as revealed by studying tau/TDP-43 droplets
2026-02-11 Exploratory analyses of clinical outcomes from the BIIB080 phase 1b study in mild Alzheimer’s disease
2026-02-07 Direct observation and quantification of single nanocondensates of the low complexity domain of TDP-43
2026-02-07 In silico discovery of natural compound-derived multi-target inhibitor for Huntington’s disease therapy
2026-02-06 Proximity proteomics reveals OTUD6B regulation of stress granule dynamics through coalescence with VCP/p97
2026-02-05 Precision estimates of longitudinal brain aging capture unexpected individual differences in one year
2026-02-05 Repurposing of natural products for spinocerebellar ataxia type 3 using integrated network pharmacology and in silico approaches
2026-01-29 Aberrant maintenance of developmental transcription factor PAX6 promotes neuronal cell death via JNK3 signaling
2026-01-27 Systematic evaluation of mitochondrial morphology regulators for amelioration of neuronal α-synucleinopathy
2026-01-23 Cytoplasmic TDP-43 leads to early behavioral impairments without neurodegeneration in a serotonergic neuron-specific C. elegans model
2026-01-21 From TDP-43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach
2026-01-21 Inhibition of de novo ceramide synthesis mitigates alpha-synuclein pathology in a Parkinson’s disease mouse model
2026-01-19 Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation
2026-01-17 Differentially expressed miRNAs in the temporal cortex of Alzheimer’s disease patients and their association to tau pathology
2026-01-16 Association of choroid plexus volume with brain atrophy and glucose metabolism in multiple system atrophy
2026-01-15 Early retinal synaptic dysfunction and proteomic remodeling precede neurodegeneration in a Parkinson’s disease model
2026-01-13 Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease